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EGFR-HER2 inhibitor Epertinib hydrochloride, Purity ≥98%
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Cat. No.: X24-05-ZQ686

EGFR-HER2 inhibitor Epertinib hydrochloride, Purity ≥98%

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Synonym: 2071195-74-7; S-22611 hydrochloride; S22611; S 22611; EGFR-HER2 inhibitor

  • CAS Number: 2071195-74-7
  • Compound CID: 139290994
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Epertinib hydrochloride, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, HER2 and HER4.
Molecular Weight
596.48
Molecular Formula
C30H28Cl2FN5O3
Targets
EGFR: 1.48 ± 0.0 nM; HER2: 7.15 ± 0.5 nM; HER4: 2.49 ± 0.1 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 88 mg/mL (147.53 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Epertinib hydrochloride can be utilized to investigate its dual inhibitory roles on EGFR and HER2 in oncology research.
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