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EGFR-HER2 inhibitor Tyrphostin AG-528, Purity ≥98%
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Cat. No.: X24-05-ZQ669

EGFR-HER2 inhibitor Tyrphostin AG-528, Purity ≥98%

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Synonym: 133550-49-9; Tyrphostin B66; EGFR-HER2 inhibitor

  • CAS Number: 133550-49-9
  • Compound CID: 1838043
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Tyrphostin AG-528, soluble in DMSO, water and ethanol, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR and ErbB2.
Molecular Weight
306.32
Molecular Formula
C18H14N2O3
Targets
EGFR: 4.9 μM; ErbB2: 2.1 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 60 mg/mL (195.87 mM); Water: <1 mg/mL; Ethanol: 5 mg/mL (16.32 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Tyrphostin AG-528 can be used to study its EGFR inhibitory effects in cancer research.
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