Cat. No.: X24-05-ZQ655
EGFR-HER2 inhibitor WHI-P180, Purity ≥98%
Synonym: 211555-08-7; Janex 3; WHI-P 180; EGFR-HER2 inhibitor
- CAS Number: 211555-08-7
- Compound CID: 5687
Product Size
5 mg; 10 mg; 25 mg
Properties
Description
WHI-P180, soluble in DMSO and insoluble in ethanol and water, is a compound that blocks the activity of the epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (HER2), both of which are involved in driving the growth and proliferation of certain types of cancer cells. It targets EGFR, KDR, and RET.
Molecular Formula
C16H15N3O3
Targets
EGFR: 4 μM; KDR: 66 nM; RET: 5 nM
Solubility
DMSO: 51 mg/mL (171.53 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
WHI-P180 is utilized in studies targeting EGFR inhibition and its impact on cancer cell signaling.
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