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FAK inhibitor NVP-TAE 226, Purity ≥98%
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Cat. No.: X24-06-ZQ487

FAK inhibitor NVP-TAE 226, Purity ≥98%

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Synonym: 761437-28-9; FAK inhibitor; TAE226; TAE 226

  • MDL: MFCD12031516
  • CAS Number: 761437-28-9
  • Compound CID: 9934347
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
NVP-TAE 226, soluble in DMSO and insoluble in ethanol and water, is a FAK inhibitor that is used to block angiogenesis in diseases such as cancer. It targets FAK, Insulin receptor, c-Abl, c-Met, C-Raf, c-Src, CDK1/CyclinB, FGFR1, FGFR3 (K650E), FLT1, and FLT3.
Molecular Weight
468.94
Molecular Formula
C23H25ClN6O3
Targets
FAK: 5.5 nM; Insulin receptor: 43.5 nM; c-Abl: 5.85 nM; c-Met: 160 nM; C-Raf: >10 μM; c-Src: 905 nM; CDK1/CyclinB: 540 nM; FGFR1: 750 nM; FGFR3 (K650E): 630 nM; FLT1: 3.4 nM; FLT3: 480 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 93 mg/mL (198.32 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
NVP-TAE 226 is a FAK inhibitor used to understand its role in cancer cell survival and metastasis.
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