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FXR inhibitor, AMG-333, Purity ≥98%
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Cat. No.: X24-09-YM316

FXR inhibitor, AMG-333, Purity ≥98%

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Synonym: 1416799-28-4; AMG333; AMG 333; 6-[[(S)-(3-Fluoropyridin-2-yl)-[3-fluoro-4-(trifluoromethoxy)phenyl]methyl]carbamoyl]pyridine-3-carboxylic acid; FXR inhibitor

  • CAS Number: 1416799-28-4
  • Compound CID: 71144018
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Product Size
2 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AMG-333, soluble in DMSO and ethanol and insoluble in water, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting FXR. The molecular weight of the compound is 453.32, and its molecular formula is C20H12F5N3O4.
Molecular Weight
453.32
Molecular Formula
C20H12F5N3O4
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 81 mg/mL (178.68 mM); Water: insoluble; Ethanol: 81 mg/mL (178.68 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG-333 plays a key role in modulating bile acid metabolism and improving liver health.
Publications
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