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Cat. No.: X23-12-YM849

Glasdegib

Synonym: 1095173-27-5; PF-4449913; PF04449913

  • CAS Number: 1095173-27-5
  • Compound CID: 25166913
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
Glasdegib (PF-04449913), soluble in DMSO and insoluble in water and ethanol, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets Smoothened.
Molecular Weight
374.18
Molecular Formula
C21H22N6O
Targets
Smoothened: 5 nM
Form
Lyophilized powder
Purity
>98%
Solubility
DMSO: 46 mg/mL (122.85 mM); Water: insoluble; Ethanol: insoluble
Applications
Glasdegib can be studied for its effect on blocking a specific signaling pathway that is overactive in certain types of cancer cells, including AML cells.
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