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GPR inhibitor APD668, Purity ≥98%
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Cat. No.: X24-06-ZQ577

GPR inhibitor APD668, Purity ≥98%

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Synonym: 832714-46-2; GPR inhibitor; APD 668; APD-668; JNJ-28630368; JNJ28630368; JNJ 28630368

  • MDL: MFCD12032117
  • CAS Number: 832714-46-2
  • Compound CID: 11705608
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
APD668, soluble in DMSO and ethanol and insoluble in water, is a compound that specifically targets and inhibits G protein-coupled receptors (GPRs), which play a critical role in transmitting signals across cell membranes. It targets CYP2C9, hERG channel, hGPR119, and rGPR119.
Molecular Weight
477.51
Molecular Formula
C21H24FN5O5S
Targets
CYP2C9: 0.1 μM (Ki); hERG channel: 3 μM; hGPR119: 2.7 μM; rGPR119: 33 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 86 mg/mL (180.1 mM); Water: Insoluble; Ethanol: 86 mg/mL (180.1 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
APD668 is studied in the context of its inhibitory effects on certain GPR receptors, relevant to diabetes and metabolic research.
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