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GSK-3 inhibitor CHIR-99021 monohydrochloride, Purity ≥98%
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Cat. No.: X24-05-ZQ261

GSK-3 inhibitor CHIR-99021 monohydrochloride, Purity ≥98%

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Synonym: 1797989-42-4; CHIR99021; CHIR 99021; CT99021 monohydrochloride; CT 99021; CT-99021; GSK-3 inhibitor

  • CAS Number: 1797989-42-4
  • Compound CID: 71295844
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CHIR-99021 monohydrochloride, soluble in DMSO and ethanol and insoluble in water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets cdc2, GSK-3α, and GSK-3β.
Molecular Weight
501.8
Molecular Formula
C22H19Cl3N8
Targets
cdc2: 8800 nM; GSK-3α: 10 nM; GSK-3β: 6.7 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 89 mg/mL (177.36 mM); Water: Insoluble; Ethanol: 2 mg/mL (3.98 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CHIR-99021 monohydrochloride is used to study GSK-3 inhibition in cellular differentiation.
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