CHIR-99021 trihydrochloride modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets cdc2, GSK-3α, and GSK-3β.
Molecular Weight
574.72
Molecular Formula
C22H21Cl5N8
Targets
cdc2: 8800 nM; GSK-3α: 10 nM; GSK-3β: 6.7 nM
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
CHIR-99021 trihydrochloride is employed in research on GSK-3 inhibition and cell fate decisions.
Publications
Publications (0)
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Publications
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