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GSK-3 inhibitor Indirubin-3-monoxime, Purity ≥98%
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Cat. No.: X24-05-ZQ270

GSK-3 inhibitor Indirubin-3-monoxime, Purity ≥98%

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Synonym: 160807-49-8; INDIRUBIN-3'-MONOXIME; Indirubin-3'-oxime; Indirubin-3-monoxime; Indirubin-3-oxime; GSK-3 inhibitor

  • CAS Number: 160807-49-8
  • Compound CID: 3707
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Product Size
5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Indirubin-3-monoxime, soluble in DMSO and insoluble in ethanol and water, modulates various cellular processes, including glucose metabolism, inflammation, and cell proliferation, with potential applications in treating diseases like diabetes and neurodegenerative disorders. It targets 5-LOX, CDK1/cyclin B, CDK5/p25, and GSK-3β.
Molecular Weight
277.28
Molecular Formula
C16H11N3O2
Targets
5-LOX: 7.8-10 μM; CDK1/cyclin B: 180 μM; CDK5/p25: 100 μM; GSK-3β: 22 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 53 mg/mL (191.14 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Indirubin-3-monoxime is used to analyze its role in inhibiting GSK-3 and cell growth.
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