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HIF inhibitor FG-2216, Purity ≥98%
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Cat. No.: X24-06-ZQ451

HIF inhibitor FG-2216, Purity ≥98%

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Synonym: 223387-75-5; HIF inhibitor; YM-311

  • MDL: MFCD23136998
  • CAS Number: 223387-75-5
  • Compound CID: 6914666
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
FG-2216, soluble in DMSO and insoluble in ethanol and water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth. It targets PHD2.
Molecular Weight
280.66
Molecular Formula
C12H9ClN2O4
Targets
PHD2: 3.9 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 48 mg/mL (171.02 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
FG-2216 acts as a HIF inhibitor, employed in research focusing on anemia and ischemic diseases.
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