Properties
Description
MK-8617, soluble in warmed DMSO and ethanol and insoluble in water, is designed to disrupt the hypoxia-inducible factor (HIF) pathway, aiming to hinder cancer cell survival and adaptation in low-oxygen environments characteristic of tumor growth.
Molecular Formula
C24H21N5O4
Solubility
Warmed DMSO: 17 mg/mL (38.34 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.25 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MK-8617 serves as a HIF inhibitor, used in exploring anemia and other hypoxia-related conditions.