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HMT inhibitor CM-272, Purity ≥98%
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Cat. No.: X24-05-ZQ502

HMT inhibitor CM-272, Purity ≥98%

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Synonym: 1846570-31-7; CM272; CM 272; Histone methyltransferase inhibitor

  • CAS Number: 1846570-31-7
  • Compound CID: 118607432
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CM-272, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets DNMT1, DNMT3A, DNMT3B, and G9a.
Molecular Weight
478.63
Molecular Formula
C28H38N4O3
Targets
DNMT1: 382 nM; DNMT3A: 85 nM; DNMT3B: 1200 nM; G9a: 8 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 95 mg/mL (198.48 mM); Water: Insoluble; Ethanol: 95 mg/mL (198.48 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CM-272 can be used to inhibit both G9a and DNMT1, impacting both histone and DNA methylation.
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