Cat. No.: X24-05-ZQ503
HMT inhibitor CM-579, Purity ≥98%
Synonym: 1846570-40-8; CM579; CM 579; Histone methyltransferase inhibitor
- CAS Number: 1846570-40-8
- Compound CID: 118613729
Product Size
5 mg; 10 mg; 50 mg; 100 mg
Properties
Description
CM-579 inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets DNA methyltransferase, DNMT1, DNMT3A, DNMT3B, and G9a.
Molecular Formula
C29H40N4O3
Targets
DNA methyltransferase: 32 nM; DNMT1: 1.5 nM; DNMT3A: 92 nM; DNMT3B: 1000 nM; G9a: 16 nM
Identity
Confirmed by NMR/HPLC/MS.
Applications
CM-579 can be used as an inhibitor of both G9a and DNMT1 for studying epigenetic modifications.
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