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HMT inhibitor CPI-169, Purity ≥98%
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Cat. No.: X24-05-ZQ505

HMT inhibitor CPI-169, Purity ≥98%

Synonym: 1450655-76-1; CPI 169; CPI169; Histone methyltransferase inhibitor

  • CAS Number: 1450655-76-1
  • Compound CID: 78357814
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
MSDS
Properties
Description
CPI-169, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH1, EZH2 WT, and EZH2 Y641N.
Molecular Weight
528.66
Molecular Formula
C27H36N4O5S
Targets
EZH1: 6.1 nM; EZH2 WT: 0.24 nM; EZH2 Y641N: 0.51 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 88 mg/mL (166.45 mM); Water: Insoluble; Ethanol: 88 mg/mL (166.45 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
CPI-169 can be used to inhibit EZH2, thereby affecting gene silencing and potential cancer pathways.
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