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HMT inhibitor EPZ005687, Purity ≥98%
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Cat. No.: X24-05-ZQ514

HMT inhibitor EPZ005687, Purity ≥98%

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Synonym: 1396772-26-1; EPZ-005687; Histone methyltransferase inhibitor

  • CAS Number: 1396772-26-1
  • Compound CID: 60160561
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
EPZ005687, soluble in DMSO and insoluble in ethanol and water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH2.
Molecular Weight
539.67
Molecular Formula
C32H37N5O3
Targets
EZH2: 24 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 2 mg/mL (3.7 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
EPZ005687 can be used to inhibit EZH2, affecting H3K27 methylation and gene expression modulation.
Publications
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