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HMT inhibitor GSK343, Purity ≥98%
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Cat. No.: X24-05-ZQ520

HMT inhibitor GSK343, Purity ≥98%

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Synonym: 1346704-33-3; GSK-343; GSK 343; Histone methyltransferase inhibitor

  • CAS Number: 1346704-33-3
  • Compound CID: 71268957
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
GSK343, soluble in warmed DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH1 and EZH2.
Molecular Weight
541.69
Molecular Formula
C31H39N7O2
Targets
EZH1: 240 nM; EZH2: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 1 mg/mL (1.84 mM); Water: Insoluble; Ethanol: 3 mg/mL (5.54 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
GSK343 can be used to inhibit EZH2 and study its effects on histone modification and cancer pathways.
Publications
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