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Cat. No.: X24-05-ZQ572

HMT inhibitor MG149, Purity ≥98%

Synonym: 1243583-85-8; MG 149; MG-149; Histone methyltransferase inhibitor

  • CAS Number: 1243583-85-8
  • Compound CID: 49864204
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Product Size
5 mg; 10 mg; 25 mg
Price
Datasheet
MSDS
Properties
Description
MG149, soluble in DMSO and ethanol and insoluble in water, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription. It targets MOF and Tip60.
Molecular Weight
340.46
Molecular Formula
C22H28O3
Targets
MOF: 47 μM; Tip60: 74 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 63 mg/mL (185.03 mM); Water: Insoluble; Ethanol: 63 mg/mL (185.03 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MG149 can be used to inhibit histone acetyltransferases KAT5 and MOZ, useful in leukemia research.
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