Cat. No.: X24-05-ZQ525
HMT inhibitor MI-2, Purity ≥98%
Synonym: 1271738-62-5; Menin-MLL inhibitor 2; Histone methyltransferase inhibitor
- CAS Number: 1271738-62-5
- Compound CID: 54765302
Product Size
5 mg; 10 mg; 25 mg
Properties
Description
MI-2, soluble in warmed DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets Menin-MLL and Menin-MLL.
Molecular Formula
C18H25N5S2
Targets
Menin-MLL; Menin-MLL: 446 nM
Solubility
Warmed DMSO: 71 mg/mL (189.05 mM); Water: Insoluble; Ethanol: 71 mg/mL (189.05 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
MI-2 can be used to inhibit Menin-MLL interaction, affecting leukemogenesis driven by MLL fusion proteins.
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