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HMT inhibitor UNC-1999, Purity ≥98%
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Cat. No.: X24-05-ZQ542

HMT inhibitor UNC-1999, Purity ≥98%

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Synonym: 1431612-23-5; UNC 1999; UNC1999; Histone methyltransferase inhibitor

  • CAS Number: 1431612-23-5
  • Compound CID: 72551585
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
UNC-1999, soluble in DMSO and ethanol and insoluble in water, inhibits the enzymes that add methyl groups to histone proteins, altering chromatin structure and gene expression. It targets EZH1 and EZH2.
Molecular Weight
569.74
Molecular Formula
C33H43N7O2
Targets
EZH1: 45 nM; EZH2: 2 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 17 mg/mL (29.84 mM); Water: Insoluble; Ethanol: 43 mg/mL (75.47 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
UNC-1999 can be used to inhibit EZH2/1, probing their role in trimethylating H3K27 and its relevance in cancer.
Publications
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