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HMT inhibitor YF-2, Purity ≥98%
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Cat. No.: X24-05-ZQ579

HMT inhibitor YF-2, Purity ≥98%

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Synonym: 1311423-89-8; YF2; YF 2; Histone methyltransferase inhibitor

  • CAS Number: 1311423-89-8
  • Compound CID: 53230697
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
YF-2, soluble in DMSO, water and ethanol, inhibits enzymes that add acetyl groups to histones, affecting chromatin structure and regulating gene transcription. It targets CBP, GCN5, and GCN5/PCAF.
Molecular Weight
430.85
Molecular Formula
C20H22ClF3N2O3
Targets
CBP: 2.75 μM (EC50); GCN5: 49.31 μM (EC50); GCN5/PCAF: 29.04 μM (EC50)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 78 mg/mL (181.03 mM); Water: 78 mg/mL (181.03 mM); Ethanol: 78 mg/mL (181.03 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
YF-2 can be used to inhibit histone acetyltransferases p300/CBP, aiding in cancer research.
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