Cat. No.: X24-09-YM089
HSP inhibitor, KNK437, Purity ≥98%
Synonym: 218924-25-5; KNK-437; KNK 437; (3E)-3-(1,3-Benzodioxol-5-ylmethylidene)-2-oxopyrrolidine-1-carbaldehyde; HSP inhibitor
- CAS Number: 218924-25-5
- Compound CID: 46195007
Product Size
10 mg; 20 mg; 50 mg; 100 mg
Properties
Description
KNK437, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 245.23, and its molecular formula is C13H11NO4.
Molecular Formula
C13H11NO4
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO (warmed): 14 mg/mL (57.08 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + corn oil,1 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
KNK437 plays a key role in enhancing cancer cell apoptosis and improving response to other therapeutic interventions.
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