HSP inhibitor, NMS-E973, Purity ≥98%

Synonym: 1253584-84-7; NMS E973; NMSE973; 5-[2,4-Dihydroxy-6-(4-nitrophenoxy)phenyl]-N-(1-methylpiperidin-4-yl)-1,2-oxazole-3-carboxamide; HSP inhibitor

CAS Number: 1253584-84-7
Compound CID: 135566652

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

NMS-E973, soluble in DMSO and insoluble in water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 454.43, and its molecular formula is C₂₂H₂₂N₄O₇. It targets the HSP90.

Molecular Weight

454.43

Molecular Formula

C₂₂H₂₂N₄O₇

Targets

HSP90

Form

Lyophilized powder

Purity

Impurities

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.

Solubility

In vitro: DMSO (warmed): 78 mg/mL (171.64 mM); Water: insoluble; Ethanol: insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

NMS-E973 plays a key role in destabilizing several oncoproteins involved in cancer cell proliferation and survival, thus offering a potential therapeutic benefit in managing cancer.