Cat. No.: X24-09-YM070
HSP inhibitor, PU-H71, Purity ≥98%
Synonym: 873436-91-0; PUH71; 8-[(6-Iodo-1,3-benzodioxol-5-yl)sulfanyl]-9-[3-(propan-2-ylamino)propyl]purin-6-amine; HSP inhibitor
- CAS Number: 873436-91-0
- Compound CID: 9549213
Product Size
5 mg; 10 mg; 25 mg; 50 mg
Properties
Description
PU-H71, soluble in DMSO, water and ethanol, is an effective metabolism inhibitor, that has the ability to prevent the pathway of cell metabolism by inhibiting HSP. The molecular weight of the compound is 512.37, and its molecular formula is C18H21IN6O2S. It targets the HSP90.
Molecular Formula
C18H21IN6O2S
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 86 mg/mL (167.85 mM); Water (warmed): 29 mg/mL (56.59 mM); Ethanol: 86 mg/mL (167.85 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PU-H71 plays a key role in inhibiting Hsp90, it leads to the degradation of multiple client proteins involved in cancer cell growth, survival, and metastasis.
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