Cat. No.: X23-10-ZQ753
IKK/IκB inhibitor Bardoxolone methyl, Purity ≥98%
Synonym: Bardoxolone methyl; 218600-53-4; CDDO-Me; CDDO methyl ester; RTA 402; NSC 713200; CDDO-Methyl ester; IKK/IκB inhibitor
- CAS Number: 218600-53-4
- Compound CID: 400769
Product Size
25 mg; 50 mg; 100 mg; 200 mg
Properties
Description
Bardoxolone methyl, soluble in DMSO and insoluble in ethanol and water, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets IKK.
Molecular Formula
C32H43NO4
Solubility
DMSO: 21 mg/mL (41.52 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
Bardoxolone methyl can be used to investigate its antioxidant and anti-inflammatory properties via activation of Nrf2 in chronic kidney disease and cancer research.
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