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Cat. No.: X23-10-ZQ524

IKK/IκB inhibitor MRT67307, Purity ≥98%

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Synonym: MRT67307; 1190378-57-4; MRT-67307; MEY37JZ4XR; N-[3-[[5-Cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide; UNII-MEY37JZ4XR; IKK/IκB inhibitor

  • CAS Number: 1190378-57-4
  • Compound CID: 44464263
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
MRT67307, soluble in warmed DMSO, water and ethanol, modulates IKK-IκB signaling pathway, which plays a key role in inflammation and immune responses. It targets Autophagy, IKKε, TBK1, ULK1, and ULK2.
Molecular Weight
464.6
Molecular Formula
C26H36N6O2
Targets
Autophagy; IKKε: 160 nM (At 0.1 mM ATP); TBK1: 19 nM (At 0.1 mM ATP); ULK1: 45 nM; ULK2: 38 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 87 mg/mL; Water: 87 mg/mL; Ethanol: 87 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
MRT67307 can be used to investigate the inhibition of IκB kinase and its role in NF-κB pathway signaling.
Publications
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