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Integrin inhibitor, Cilengitide trifluoroacetate, Purity ≥98%

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Cat. No.: X24-08-YM282

Integrin inhibitor, Cilengitide trifluoroacetate, Purity ≥98%

Synonym: 199807-35-7; EMD 12197; EMD-85189; EMD-121974; NSC-707544; D03497; 2-[(2S,5R,8S,11S)-5-Benzyl-11-[3-(diaminomethylideneamino)propyl]-7-methyl-3,6,9,12,15-pentaoxo-8-propan-2-yl-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid; 2,2,2-trifluoroacetic acid

MDL: MFCD22665738
CAS Number: 199807-35-7
Compound CID: 129626550

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

Cilengitide trifluoroacetate, soluble in DMSO and water and insoluble in ethanol, is an effective cytoskeleton inhibitor, that has the ability to prevent the pathway of cytoskeletal signaling by inhibiting integrin. It targets the αvβ3 receptor (cell-free assay) and αvβ5 receptor (cell-free assay).

Molecular Weight

702.7

Molecular Formula

C₂₉H₄₁N₈O₉F₃

Targets

αvβ3 Receptor (Cell-free assay): 4.1 nM; αvβ5 Receptor (Cell-free assay): 79 nM

Form

Lyophilized powder

Purity

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 89 mg/mL (126.66 mM); Water: 7 mg/mL (9.96 mM); Ethanol: insoluble

Applications

Cilengitide trifluoroacetate is a cytoskeletal signaling inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers by inhibiting integrin-mediated cell adhesion and tumor angiogenesis.

Publications

Publications (0)

Publications

Publications

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