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JNK-c-Jun inhibitor IQ 3, Purity ≥98%
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Cat. No.: X23-10-ZQ943

JNK-c-Jun inhibitor IQ 3, Purity ≥98%

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Synonym: 312538-03-7; IQ-3; [(E)-Indeno[1,2-b]quinoxalin-11-ylideneamino] furan-2-carboxylate; 11H-Indeno[1,2-b]quinoxalin-11-one O-(2-furanylcarbonyl)oxime; JNK-c-Jun inhibitor

  • CAS Number: 312538-03-7
  • Compound CID: 5405540
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
IQ 3, soluble in DMSO and insoluble in ethanol and water, is an inhibitor of c-jun N-terminal kinase (JNK) signaling. It targets CK1δ, JNK1, JNK2, and JNK3.
Molecular Weight
341.32
Molecular Formula
C20H11N3O3
Targets
CK1δ: 0.56 μM (Kd); JNK1: 0.24 μM (Kd); JNK2: 0.29 μM (Kd); JNK3: 0.066 μM (Kd)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 9 mg/mL (26.36 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
IQ 3 can be utilized to study molecular pathways involving protein kinases inhibited by IQ 3.
Publications
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