Properties
Description
Levosimendan, soluble in DMSO and insoluble in water and ethanol, is a Ca2+ sensitizer that increases the contractile force of the myocardium. The molecular weight of the compound is 280.29, and its molecular formula is C14H12N6O.
Molecular Formula
C14H12N6O
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 48 mg/mL (171.26 mM); Water: insoluble; Ethanol: insoluble; In vivo: 5% DMSO + 40% PEG 300 + 5% Tween80 + 50% ddH2O, 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Levosimendan plays a key role in increasing intracellular calcium levels, which reduces the risk of calcium overload.