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MDM2 inhibitor AMG232, Purity ≥98%
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Cat. No.: X23-10-ZQ137

MDM2 inhibitor AMG232, Purity ≥98%

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Synonym: 1352066-68-2; KRT-232; AMG-232; Navtemadlin; AMG 232; AMG232; 2-((3R,5R,6S)-5-(3-Chlorophenyl)-6-(4-chlorophenyl)-1-((S)-1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic acid; MDM2 inhibitor

  • CAS Number: 1352066-68-2
  • Compound CID: 58573469
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
AMG232 prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells.
Molecular Weight
568.55
Molecular Formula
C28H35Cl2NO5S
Form
Lyophilized powder
Purity
≥98%
Identity
Confirmed by NMR/HPLC/MS.
Applications
AMG232 can be employed to investigate the pharmacological effects of MDM2 inhibition in p53-expressing tumors.
Publications
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