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MDM2 inhibitor Idasanutlin, Purity ≥98%
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Cat. No.: X23-10-ZQ135

MDM2 inhibitor Idasanutlin, Purity ≥98%

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Synonym: 1229705-06-9; Idasanutlin; RG7388; RG-7388; Idasanutlin (RG-7388); Idasanutlin (RG7388); RO5503781; 4-((2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid; MDM2 inhibitor

  • MDL: MFCD26142931
  • CAS Number: 1229705-06-9
  • Compound CID: 53358942
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Idasanutlin, soluble in DMSO and warmed ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets Mdm2.
Molecular Weight
616.48
Molecular Formula
C31H29Cl2F2N3O4
Targets
Mdm2
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 88 mg/mL (142.74 mM); Water: Insoluble; Warmed ethanol: 7 mg/mL (11.35 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Idasanutlin can be utilized in cancer research to inhibit MDM2 and stabilize p53, promoting tumor cell apoptosis.
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