NSC-207895, soluble in DMSO and insoluble in ethanol and water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets p53 and MDMX.
NSC-207895 can be used to enhance p53 activity by inhibiting MDM2-p53 interactions in cancer cells.
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