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MDM2 inhibitor SAR-405838, Purity ≥98%
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Cat. No.: X23-10-ZQ131

MDM2 inhibitor SAR-405838, Purity ≥98%

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Synonym: 1303607-60-4; SAR405838; MI-77301; SAR-405838; MI-773 (SAR405838); 8570LZ3RCA; MDM2 inhibitor

  • MDL: MFCD28976052
  • CAS Number: 1303607-60-4
  • Compound CID: 53476877
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Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
SAR-405838, soluble in DMSO and warmed ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets p53 and MDM2.
Molecular Weight
562.5
Molecular Formula
C29H34Cl2FN3O3
Targets
p53; MDM2: 0.88 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 93 mg/mL (165.33 mM); Water: Insoluble; Warmed ethanol: 29 mg/mL (51.55 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
SAR-405838 can be used to study p53-MDM2 interaction and its potential as a cancer therapeutic by activating p53-mediated apoptotic pathways.
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