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MDM2 inhibitor YH239-EE, Purity ≥98%
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Cat. No.: X23-10-ZQ136

MDM2 inhibitor YH239-EE, Purity ≥98%

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Synonym: 1364488-67-4; YH239-EE; Ethyl 3-(2-(tert-butylamino)-1-(N-(4-chlorobenzyl)formamido)-2-oxoethyl)-6-chloro-1H-indole-2-carboxylate; Ethyl 3-[2-(tert-butylamino)-1-[N-(4-chlorobenzyl)formamido]-2-oxoethyl]-6-chloro-1H-indole-2-carboxylate; MDM2 inhibitor

  • CAS Number: 1364488-67-4
  • Compound CID: 56943013
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
YH239-EE, soluble in DMSO and ethanol and insoluble in water, prevents the degradation of p53 by inhibiting the MDM2-p53 interaction, leading to increased p53 levels and promoting apoptosis in p53-responsive cells. It targets p53/MDM2.
Molecular Weight
504.41
Targets
p53/MDM2
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 85 mg/mL (168.51 mM); Water: Insoluble; Ethanol: 15 mg/mL (29.73 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
YH239-EE can be used to study the inhibition of MDM2-p53 interaction and its therapeutic potential in cancer treatment.
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