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mTOR inhibitor INK 128, Purity ≥98%
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Cat. No.: X24-05-ZQ024

mTOR inhibitor INK 128, Purity ≥98%

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Synonym: 1224844-38-5; INK128; INK-128; MLN0128; mTOR inhibitor

  • CAS Number: 1224844-38-5
  • Compound CID: 45375953
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
INK 128, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR, PI3Kα, mTOR, PI3Kβ, PI3Kδ, and PI3Kγ.
Molecular Weight
309.3
Molecular Formula
C15H15N7O
Targets
mTOR: 1.4 nM (Ki); PI3Kα: 219 nM; mTOR: 1.4 nM (Ki); PI3Kβ: 5293 nM; PI3Kδ: 230 nM; PI3Kγ: 221 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 58 mg/mL (187.5 mM); Water: Insoluble; Ethanol: 2 mg/mL (6.46 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
INK 128 can be used to study its role as an mTORC1 and mTORC2 inhibitor in cancer and other diseases.
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