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mTOR inhibitor PP242, Purity ≥98%

Cat. No.: X24-05-ZQ044

mTOR inhibitor PP242, Purity ≥98%

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Synonym: 1092351-67-1; PP-242; Torkinib; mTOR inhibitor

  • CAS Number: 1092351-67-1
  • Compound CID: 135565635
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
PP242, soluble in DMSO and ethanol and insoluble in water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets DNA-PK, p110δ, Abl, EGFR, EphB4, Hck, mTOR, p110α, p110β, p110γ, and PDGFR.
Molecular Weight
308.3
Molecular Formula
C16H16N6O
Targets
DNA-PK: 0.41 μM; p110δ: 0.10 μM; Abl: 3.6 μM; EGFR: 4.4 μM; EphB4: 3.4 μM; Hck: 1.2 μM; mTOR: 8 μM; p110α: 2.0 μM; p110β: 2.2 μM; p110γ: 1.3 μM; PDGFR: 0.41 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 57 mg/mL (184.86 mM); Water: Insoluble; Ethanol: 17 mg/mL (55.13 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
PP242 is utilized in studies examining the inhibition of mTORC1 and mTORC2 in cellular growth and cancer.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
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Cyclodextrin
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Dextran
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