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Cat. No.: X24-05-ZQ059

mTOR inhibitor WYE-354, Purity ≥98%

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Synonym: 1062169-56-5; WYE354; mTOR inhibitor

  • CAS Number: 1062169-56-5
  • Compound CID: 44219749
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
WYE-354, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets PI3Kα, PI3Kγ, Abl1, AuroraB, CDK1/CyclinB, CDK2/CyclinA, Chk1, ERK2, Fyn, GCK, and Hck.
Molecular Weight
495.5
Molecular Formula
C24H29N7O5
Targets
PI3Kα: 1.89 μM; PI3Kγ: 7.37 μM; Abl1: >50 μM; AuroraB: >50 μM; CDK1/CyclinB: >50 μM; CDK2/CyclinA: >50 μM; Chk1: >50 μM; ERK2: >50 μM; Fyn: >50 μM; GCK: >50 μM; Hck: >50 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 95 mg/mL (191.71 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
WYE-354 is used to investigate its role as an mTOR inhibitor, helping scientists understand mTOR-dependent cellular processes and potential cancer therapies.
Publications
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