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mTOR inhibitor WYE-687, Purity ≥98%
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Cat. No.: X24-05-ZQ060

mTOR inhibitor WYE-687, Purity ≥98%

Synonym: 1062161-90-3; WYE687; mTOR inhibitor

  • CAS Number: 1062161-90-3
  • Compound CID: 25229450
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
MSDS
Properties
Description
WYE-687, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets PI3Kα, PI3Kγ, Abl1, AuroraB, CDK1/CyclinB, CDK2/CyclinA, Chk1, ERK2, Fyn, GCK, and Hck.
Molecular Weight
528.61
Molecular Formula
C28H32N8O3
Targets
PI3Kα: 0.81 μM; PI3Kγ: 3.11 μM; Abl1: >50 μM; AuroraB: >50 μM; CDK1/CyclinB: >50 μM; CDK2/CyclinA: >50 μM; Chk1: >50 μM; ERK2: >50 μM; Fyn: >50 μM; GCK: >50 μM; Hck: >50 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 0.45 mg/mL (0.85 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
WYE-687 is employed in scientific studies as an mTOR kinase inhibitor to explore the mTOR signaling cascade and its implications in cancer and metabolic diseases.
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