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mTOR inhibitor XL388, Purity ≥98%

Cat. No.: X24-05-ZQ061

mTOR inhibitor XL388, Purity ≥98%

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Synonym: 1251156-08-7; XL 388; XL-388; mTOR inhibitor

  • CAS Number: 1251156-08-7
  • Compound CID: 59604787
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Product Size
5 mg; 10mg; 25 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
XL388, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR, mTORC2, CYP2C8, CYP2C9, CYP2D6, CYP3A4, mTORC1, and PI3Kα.
Molecular Weight
455.5
Molecular Formula
C23H22FN3O4S
Targets
mTOR: 9.9 nM; mTORC2: 166 nM; CYP2C8: >20 μM; CYP2C9: 10.6 μM; CYP2D6: >20 μM; CYP3A4: 24.6 μM; mTORC1: 8 nM; PI3Kα: >3 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 21 mg/mL (46.1 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
XL388 is used to study the inhibition of mTOR kinase and its effects on cell growth, proliferation, and survival, particularly in cancerous cells.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
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Cyclodextrin
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Dextran
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