XL388, soluble in DMSO and insoluble in ethanol and water, disrupts cell growth, proliferation, and survival by targeting a key component of cellular signaling pathways. It targets mTOR, mTORC2, CYP2C8, CYP2C9, CYP2D6, CYP3A4, mTORC1, and PI3Kα.
XL388 is used to study the inhibition of mTOR kinase and its effects on cell growth, proliferation, and survival, particularly in cancerous cells.
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