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P-gp inhibitor LY335979, Purity ≥98%
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Cat. No.: X24-07-ZQ288

P-gp inhibitor LY335979, Purity ≥98%

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Synonym: 167465-36-3; P-gp inhibitor; LY-335979; Zosuquidar trihydrochloride; RS-33295-198

  • MDL: MFCD00942300
  • CAS Number: 167465-36-3
  • Compound CID: 153997
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
LY335979, soluble in DMSO and water and insoluble in ethanol, blocks the action of P-glycoprotein, a key player in drug transport and resistance, thereby enhancing the effectiveness and bioavailability of therapeutic drugs. It targets P-gp.
Molecular Weight
637
Molecular Formula
C32H31F2N3O2.3HCl
Targets
P-gp: 60 nM (Ki)
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 93 mg/mL (145.99 mM); Water: 21 mg/mL (32.96 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
LY335979 is a P-gp inhibitor utilized in cancer research to study its potential to overcome multidrug resistance in tumor cells.
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