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Paclitaxel-loaded PLGA-PEG nanoparticles (PLGA-PEG(PTX))
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Cat. No.: X26-06-ZQ5102

Paclitaxel-loaded PLGA-PEG nanoparticles (PLGA-PEG(PTX))

Synonym: PLGA-PEG(PTX); Paclitaxel-loaded PLGA-PEG nanoparticles; PLGA-PEG-PTX taxane-loaded block copolymer grains; Paclitaxel loaded PLGA PEG; PLGA-PEG(PTX) amphiphilic ester-ether nodes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
Core-shell amphiphilic polymeric nanoparticles encapsulating the highly hydrophobic chemotherapeutic agent paclitaxel (PTX) within a core of poly(lactic-co-glycolic acid) (PLGA), surrounded by a hydrophilic polyethylene glycol (PEG) outer shell. The PEG layer screens the hydrophobic PLGA core, minimizing the adsorption of opsonin proteins and evading detection by the mononuclear phagocyte system (MPS).
Source
Custom synthesis
Functional Group
Paclitaxel (PTX); PLGA
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Applications
Extended systemic circulation testing, passive tumor targeting validation via the EPR effect, and controlled hydrophobic drug release kinetics.
Publications
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