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PDE inhibitor, PF-8380, Purity ≥98%
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Cat. No.: X24-08-YM495

PDE inhibitor, PF-8380, Purity ≥98%

Synonym: 1144035-53-9; PF 8380; PF8380; (3,5-Dichlorophenyl)methyl 4-[3-oxo-3-(2-oxo-3H-1,3-benzoxazol-6-yl)propyl]piperazine-1-carboxylate

  • MDL: MFCD20527274
  • CAS Number: 1144035-53-9
  • Compound CID: 25265312
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
MSDS
Properties
Description
PF-8380, soluble in DMSO and insoluble in water and ethanol, is an effective cell metabolism inhibitor, that has the ability to prevent the pathway of metabolism by inhibiting PDE. It targets the Autotaxin.
Molecular Weight
478.33
Molecular Formula
C22H21Cl2N3O5
Targets
Autotaxin: 2.8 nM
Form
Lyophilized powder
Purity
≥98%
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 89 mg/mL (186.06 mM); Water: insoluble; Ethanol: insoluble; In vivo: 1% cmc-na, 14 mg/mL
Applications
PF-8380 is a metabolism inhibitor that can be used for its ability to enhance cognitive function and memory.
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