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PDGFR inhibitor Avapritinib, Purity ≥98%
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Cat. No.: X24-06-ZQ117

PDGFR inhibitor Avapritinib, Purity ≥98%

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Synonym: 1703793-34-3; PDGFR inhibitor; BLU-285; BLU 285; BLU285

  • MDL: MFCD31544325
  • CAS Number: 1703793-34-3
  • Compound CID: 118023034
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Product Size
1 mg; 5 mg; 10 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Avapritinib, soluble in DMSO and ethanol and insoluble in water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit, Flt3, PDGFRβ, and VEGFR2.
Molecular Weight
498.56
Molecular Formula
C26H27FN10
Targets
c-Kit: 9 nM; Flt3: 7 nM; PDGFRβ: 4 nM; VEGFR2: 8 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 61 mg/mL (122.35 mM); Water: Insoluble; Ethanol: 3 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
Avapritinib inhibits PDGFR, which is critical for research on treating tumors driven by abnormal platelet-derived growth factor receptors.
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