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PDGFR inhibitor CP-673451, Purity ≥98%
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Cat. No.: X24-06-ZQ119

PDGFR inhibitor CP-673451, Purity ≥98%

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Synonym: 343787-29-1; PDGFR inhibitor; CP673451

  • CAS Number: 343787-29-1
  • Compound CID: 10158940
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CP-673451, soluble in warmed DMSO and ethanol and insoluble in water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit, PDGFRα, bFGFR, c-Met, EGFR, ErbB2, IGF-1R, LCK, PDGFRβ, Src, and Tie-2.
Molecular Weight
417.5
Molecular Formula
C24H27N5O2
Targets
c-Kit: 252 nM; PDGFRα: 10 nM; bFGFR: >5 μM; c-Met: >10 μM; EGFR: >10 μM; ErbB2: >10 μM; IGF-1R: >10 μM; LCK: >1 μM; PDGFRβ: 1 μM; Src: >2 μM; Tie-2: >5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 28 mg/mL (67.06 mM); Water: Insoluble; Ethanol: 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
CP-673451 acts as a PDGFR inhibitor, contributing to research on pathways involved in cancerous cell proliferation.
Publications
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