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PDGFR inhibitor CP-673451, Purity ≥98%

Cat. No.: X24-06-ZQ119

PDGFR inhibitor CP-673451, Purity ≥98%

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Synonym: 343787-29-1; PDGFR inhibitor; CP673451

  • CAS Number: 343787-29-1
  • Compound CID: 10158940
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Product Size
5 mg; 10 mg; 25 mg; 50 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
CP-673451, soluble in warmed DMSO and ethanol and insoluble in water, blocks the activity of platelet-derived growth factor receptors (PDGFR), which play a crucial role in cell growth, angiogenesis, and tissue. It targets c-Kit, PDGFRα, bFGFR, c-Met, EGFR, ErbB2, IGF-1R, LCK, PDGFRβ, Src, and Tie-2.
Molecular Weight
417.5
Molecular Formula
C24H27N5O2
Targets
c-Kit: 252 nM; PDGFRα: 10 nM; bFGFR: >5 μM; c-Met: >10 μM; EGFR: >10 μM; ErbB2: >10 μM; IGF-1R: >10 μM; LCK: >1 μM; PDGFRβ: 1 μM; Src: >2 μM; Tie-2: >5 μM
Form
Lyophilized powder
Purity
≥98%
Solubility
Warmed DMSO: 28 mg/mL (67.06 mM); Water: Insoluble; Ethanol: 4 mg/mL
Identity
Confirmed by NMR/HPLC/MS.
Applications
CP-673451 acts as a PDGFR inhibitor, contributing to research on pathways involved in cancerous cell proliferation.
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O-Glycan
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Blood Group and Lewis Antigen
Blood group A trisaccharide (Cat#: XCO0060Q) Blood group B trisaccharide (Cat#: XCO0068Q) Blood group H disaccharide (Cat#: XCO0074Q) Lewis A trisaccharide (Cat#: XCO0079Q) 3'-Sulfated lewis A (Cat#: XCO0080Q) Lewis B tetrasaccharide (Cat#: XCO0083Q) Lewis X trisaccharide (Cat#: XCO0085Q) Lewis Y tetrasaccharide (Cat#: XCO0088Q)
Human Milk Oligosaccharides (HMOs)
Lacto-N-biose (Cat#: XCO0089Q) 2'-Fucosyllactose (Cat#: XCO0091Q) 3-Fucosyllactose (Cat#: XCO0092Q) Lactodifucotetraose (Cat#: XCO0093Q) Lacto-N-triose I (Cat#: XCO0094Q) 3'-Sialyllactose sodium salt (Cat#: XCO0096Q) 6'-Sialyllactose sodium salt (Cat#: XCO0098Q) 3'-Sialyl-3-fucosyllactose (Cat#: XCO0100Q)
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Heparin amine, MW 27 kDa (Cat#: X22-09-ZQ478) FITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ480) TRITC-heparin, MW 27 kDa (Cat#: X22-09-ZQ481) Biotin-heparin-FITC, MW 18 kDa (Cat#: X22-09-ZQ482) Chondroitin sulfate (dp4) (Cat#: X22-11-ZQ598) Dermatan sulfate (dp12) (Cat#: X22-11-ZQ611) Heparin disaccharide I-A (Cat#: X22-11-ZQ662) Chondroitine sulfate (Cat#: X23-04-XQ1118)
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Cyclodextrin
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Dextran
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