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PERK inhibitor ISRIB, Purity ≥98%
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Cat. No.: X23-10-ZQ161

PERK inhibitor ISRIB, Purity ≥98%

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Synonym: 1597403-47-8; 548470-11-7; 1597403-48-9; ISRIB; Trans-ISRIB; ISRIB (trans-isomer); N,N'-(cis-cyclohexane-1,4-diyl)bis(2-(4-chlorophenoxy)acetamide); PERK inhibitor

  • MDL: MFCD27952932; MFCD30730068
  • CAS Number: 1597403-47-8
  • Compound CID: 1011240
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Product Size
10 mg; 25 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
ISRIB, soluble in DMSO and insoluble in ethanol and water, disrupts UPR pathway, potentially affecting apoptosis through various downstream effects. It targets PERK.
Molecular Weight
451.34
Molecular Formula
C22H24Cl2N2O4
Targets
PERK: 5 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 4 mg/mL (8.86 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ISRIB can be employed to research the regulation of protein synthesis and stress responses in disease models.
Publications
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