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PROTAC degrader inhibitor, Gefitinib-based PROTAC 3, Purity ≥98%
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Cat. No.: X24-09-YM746

PROTAC degrader inhibitor, Gefitinib-based PROTAC 3, Purity ≥98%

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Synonym: 2230821-27-7; GTPL10636; GLXC-25268; EX-A3010; AKOS037653377; AC-36293; BP-28379; (2S,4R)-1-[(2S)-2-[3-[2-[5-[4-(3-Chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypentoxy]ethoxy]propanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide; PROTAC degrader inhibitor

  • CAS Number: 2230821-27-7
  • Compound CID: 135156947
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Product Size
5 mg; 10 mg; 50 mg; 100 mg
Price
Datasheet
Datasheet
MSDS
MSDS
Properties
Description
Gefitinib-based PROTAC 3, soluble in DMSO and ethanol and insoluble in water, is an effective PROTAC inhibitor, that has the ability to prevent the pathway of PROTAC degrader. The molecular weight of the compound is 934.51, and its molecular formula is C47H57ClFN7O8S. It targets the EGFR and EGFR.
Molecular Weight
934.51
Molecular Formula
C47H57ClFN7O8S
Targets
EGFR
Form
Lyophilized powder
Purity
≥98%
Impurities
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects.
Solubility
In vitro: DMSO: 92 mg/mL (98.44 mM); Water: insoluble; Ethanol: 92 mg/mL (98.44 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Gefitinib-based PROTAC 3 can be used for its potential to overcome resistance in EGFR-mutant cancers.
Publications
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