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Proteasome inhibitor VR23, Purity ≥98%

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Cat. No.: X24-07-ZQ769

Proteasome inhibitor VR23, Purity ≥98%

Synonym: 1624602-30-7; Proteasome inhibitor; VR-23; VR 23

MDL: MFCD28502093
CAS Number: 1624602-30-7
Compound CID: 73442847

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

MSDS

Properties

Description

VR23, soluble in warmed DMSO and warmed water and insoluble in ethanol, interferes with the proteasome’s ability to degrade proteins, thereby disrupting cellular processes in cancer cells, particularly multiple myeloma. It targets Caspase-like proteasomes, Chymotrypsin-like proteasomes, and trypsin-like proteasomes.

Molecular Weight

477.88

Molecular Formula

C₁₉H₁₆ClN₅O₆S

Targets

Caspase-like proteasomes: 3 μM; Chymotrypsin-like proteasomes: 50-100 nM; Trypsin-like proteasomes: 1 nM

Form

Lyophilized powder

Purity

Solubility

Warmed DMSO: 29 mg/mL (60.68 mM); Warmed water: 5 mg/mL (10.46 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

VR23 is used in research to investigate and inhibit proteasome activity, which is key in regulating protein degradation and cellular processes.

Publications

Publications (0)

Publications

Publications

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