EHT 1864, soluble in warmed DMSO and water and insoluble in ethanol, blocks the activity of Ras proteins, which play a key role in cell signal transduction and are frequently implicated in oncogenic mutations. It targets Rac1, Rac1b, Rac2, and Rac3.
EHT 1864 can be employed to study inhibition of Rac1 in cellular processes and cancer metastasis.
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