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ROS-responsive NBD-labeled PLGA nanoparticles (ROS-PLGA-NBD)
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Cat. No.: X26-06-ZQ4931

ROS-responsive NBD-labeled PLGA nanoparticles (ROS-PLGA-NBD)

Synonym: ROS-PLGA-NBD; ROS-responsive NBD-labeled PLGA nanoparticles; ROS-PLGA-NBD oxidation-sensitive benzofurazan spheres; ROS responsive NBD PLGA; ROS-PLGA-NBD tracking ester nodes

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Product Size
100 mg; 250 mg; 500 mg; 1 g; 5 g
Price
Datasheet
MSDS
Properties
Description
This product consists of an oxidative stress-sensitive blank PLGA core labeled with the environmentally sensitive fluorophore NBD. The polymer core degrades when exposed to reactive oxygen species. The NBD tag alters its fluorescence intensity as the surrounding polymer matrix transitions from hydrophobic to hydrophilic during degradation.
Source
Custom synthesis
Functional Group
PLGA; 7-Nitrobenzofurazan (NBD)
Form
Solid or powder
Purity
≥95%
Impurities
No visible impurities to the naked eye.
Identity
HPLC/MS/NMR
Applications
This product can be used for real-time monitoring of ROS-driven matrix erosion, sensing local polarity changes during polymer degradation, and establishing oxidation-responsive profiles.
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