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Cat. No.: X24-05-ZQ241
RSK inhibitor LJH685, Purity ≥98%
Synonym: 1627710-50-2; LJH 685; LJH-685; RSK inhibitor
- CAS Number: 1627710-50-2
- Compound CID: 73010393
Properties
Description
LJH685, soluble in DMSO and ethanol and insoluble in water, attenuates the activity of kinases involved in cell growth, survival, and proliferation, which can be utilized to inhibit tumor progression. It targets RSK1, RSK2, and RSK3.
Molecular Weight
381.42
Molecular Formula
C22H21F2N3O
Targets
RSK1: 6 nM; RSK2: 5 nM; RSK3: 4 nM
Form
Lyophilized powder
Purity
≥98%
Solubility
DMSO: 66 mg/mL (173.03 mM); Water: Insoluble; Ethanol: 17 mg/mL (44.57 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
LJH685 can be used to investigate its selective inhibition of AKT signaling pathways in cancer research.
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